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Background: |
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
TCAP |
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Immunogen: |
Fusion protein of human TCAP |
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Full name: |
titin-cap |
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Synonyms: |
TELE; CMD1N; CMH25; T-cap; LGMD2G; LGMDR7; telethonin |
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SwissProt: |
O15273 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil and Human thyroid cancer |
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IHC Recommend dilution: |
50-200 |

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