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Background: |
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
TIMP3 |
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Immunogen: |
Fusion protein of human TIMP3 |
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Full name: |
TIMP metallopeptidase inhibitor 3 |
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Synonyms: |
SFD; K222; K222TA2; HSMRK222 |
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SwissProt: |
P35625 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human thyroid cancer and Human cervical cancer |
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IHC Recommend dilution: |
15-50 |
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WB Predicted band size: |
24 kDa |
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WB Positive control: |
Huvec cells |
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WB Recommended dilution: |
200-1000 |

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