購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
This gene encodes a member of the Groucho/ transducin-like Enhancer of split family of transcriptional co-repressors. The encoded protein is a component of the mammalian subcortical maternal complex, which is required for preimplantation development. In mouse, knock out of this gene results in cleavage-stage embryonic arrest resulting from defective cytoplasmic F-actin meshwork formation and asymmetric cell division. In human, an allelic variant in this gene is associated with preimplantation embryonic lethality. Alternative splicing results in multiple transcript variants. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
TLE6 |
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Immunogen: |
Fusion protein of human TLE6 |
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Full name: |
transducin like enhancer of split 6 |
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Synonyms: |
GRG6; PREMBL |
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SwissProt: |
Q9H808 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
50-200 |
