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    • 目錄號(hào) : TW22953
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中文名稱(chēng)： 兔抗TPMT多克隆抗體

英文名稱(chēng)： Anti-TPMT rabbit polyclonal antibody

別      名： thiopurine S-methyltransferase; TPMTD

相關(guān)類(lèi)別： 一抗

儲(chǔ)      存： 冷凍（-20℃）

宿      主： Rabbit

抗      原： TPMT

反應(yīng)種屬： Human

標(biāo)  記 物： Unconjugate

克隆類(lèi)型： rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.

Applications:

ELISA, IHC

Name of antibody:

TPMT

Immunogen:

Fusion protein of human TPMT

Full name:

thiopurine S-methyltransferase

Synonyms:

TPMTD

SwissProt:

P51580

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human cervical cancer

IHC Recommend dilution:

40-200



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