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中文名稱：CHRNA3抗原

英文名稱：CHRNA3 Antigen

別    名： LNCR2, PAOD2, NACHRA3

相關(guān)類別：抗原

儲    存： 冷凍（-20℃）

概    述

Synthetic peptide corresponding to a region derived from 69-83 amino acids of human cholinergic receptor, nicotinic, alpha 3 (neuronal)

技術(shù)規(guī)格

Full name:

cholinergic receptor, nicotinic, alpha 3 (neuronal)

Synonyms:

LNCR2, PAOD2, NACHRA3

Gene Accession:

NP_000734

SwissProt:

P32297

Background:

This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.


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