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  • SASH1 抗原

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW4774
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:20
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中文名稱(chēng): SASH1 抗原

英文名稱(chēng): SASH1 Antigen

相關(guān)類(lèi)別: 抗原

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概      述

Synthetic peptide corresponding to a region derived from 78-92 amino acids of human SAM and SH3 domain containing 1

技術(shù)規(guī)格

Full name

SAM and SH3 domain containing 1

Synonyms

SH3D6A; dJ323M4; dJ323M4.1

Swissprot

O94885

Gene Accession

NP_056093

Background

SASH1 (SAM and SH3 domain-containing protein 1), also known as PEPE1 (Proline-glutamate repeat-containing protein), is a 1247 amino acid protein that is significantly downregulated in the majority of primary breast tumor tissues, breast cancer cell lines, lung and thyroid tumors, as well as in certain colon carcinomas. It has been hypothesized that its expression is suppressed not due to mutation of the SASH1 gene, but instead via other mechanisms, such as promoter methylation.