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中文名稱： SRPX 抗原（重組蛋白）

英文名稱： SRPX Antigen (Recombinant Protein)

別     名： sushi-repeat containing protein, X-linked; DRS; ETX1; SRPX1; HEL-S-83p

儲(chǔ)     存： 冷凍（-20℃）

相關(guān)類別：抗原

概     述

Fusion protein corresponding to C terminal 250 amino acids of human SRPX

技術(shù)規(guī)格

Full name:

sushi-repeat containing protein, X-linked

Synonyms:

DRS; ETX1; SRPX1; HEL-S-83p

Swissprot:

P78539

Gene Accession:

BC020684

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

SRPX gene also designated ETX1, resides within this region and is deleted in XLRP patients. There are at least two splice variants of SRPX, one of which contains a thirty amino acid signal peptide. Both variants contain three complement control protein domains, a hydrophobic region for membrane anchorage, and a cytoplasmic carboxy terminus. SRPX is expressed in retina and heart. SRPX is highly homologous to the drs (downregulated by v-src) human homolog, which suggests a role for SRPX as a tumor suppressor.


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