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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW5868
    • 應(yīng)用 : 僅供科研使用
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    • 規(guī)格 :1mg/100ug
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中文名稱(chēng): TWSG1 抗原(重組蛋白)

英文名稱(chēng): TWSG1 Antigen (Recombinant Protein)

別    名: twisted gastrulation BMP signaling modulator 1; TSG

相關(guān)類(lèi)別:抗原

儲(chǔ)     存: 冷凍(-20℃)

概     述

Fusion protein corresponding to a region derived from 26-223 amino acids of human TWSG1

技術(shù)規(guī)格

Full name:

twisted gastrulation BMP signaling modulator 1

Synonyms:

TSG

Swissprot:

Q9GZX9

Gene Accession:

BC020490

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).


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