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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW5896
    • 應(yīng)用 : 僅供科研使用
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中文名稱： U2AF2 抗原（重組蛋白）

英文名稱： U2AF2 Antigen (Recombinant Protein)

別     名： U2 small nuclear RNA auxiliary factor 2; U2AF65

相關(guān)類別：抗原

儲(chǔ)     存： 冷凍（-20℃）

概     述

Fusion protein corresponding to a region derived from 272-471 amino acids of human U2AF2

技術(shù)規(guī)格

Full name:

U2 small nuclear RNA auxiliary factor 2

Synonyms:

U2AF65

Swissprot:

P26368

Gene Accession:

BC008740

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.


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