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中文名稱：小鼠抗CSE1L單克隆抗體

英文名稱： Anti-CSE1L mouse monoclonal antibody
別       名： chromosome segregation 1 like; CAS; CSE1; XPO2
相關(guān)類別： 一抗

儲       存： 冷凍（-20℃）
宿       主： Mouse

抗      原： CSE1L
反應種屬： Human
標  記 物： Unconjugate

克隆類型： mouse monoclonal



技術(shù)規(guī)格

Background:

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene.

Applications:

WB, IHC

Name of antibody:

CSE1L

Immunogen:

Fusion protein of human CSE1L

Full name:

chromosome segregation 1 like

Synonyms:

CAS; CSE1; XPO2

SwissProt:

P55060

IHC positive control:

Human kidney cancer and Human gastric cancer

IHC Recommend dilution:

500-2000

WB Predicted band size:

110 KD

WB Positive control:

Hela, Ramos cell lysates

WB Recommended dilution:

200-1000

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