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中文名稱：小鼠抗LMNA單克隆抗體

英文名稱： Anti-LMNA mouse monoclonal antibody
別       名： lamin A/C; FPL; IDC; LFP; CDDC; EMD2; FPLD; HGPS; LDP1; LMN1; LMNC; MADA; PRO1; CDCD1; CMD1A; FPLD2; LMNL1; CMT2B1; LGMD1B
相關(guān)類別： 一抗

儲(chǔ)       存： 冷凍（-20℃）
宿       主： Mouse

抗       原： LMNA
反應(yīng)種屬： Human, Mouse, Rat
標(biāo)  記  物： Unconjugate

克隆類型： Mouse Monoclonal
技術(shù)規(guī)格

Background:

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

Applications:

WB

Name of antibody:

LMNA

Immunogen:

Fusion protein of human LMNA

Full name:

lamin A/C

Synonyms:

FPL; IDC; LFP; CDDC; EMD2; FPLD; HGPS; LDP1; LMN1; LMNC; MADA; PRO1; CDCD1; CMD1A; FPLD2; LMNL1; CMT2B1; LGMD1B

SwissProt:

P02545

WB Predicted band size:

74 kDa

WB Positive control:

K562, C6, 3T3 and Hela cell lysates

WB Recommended dilution:

1000-5000




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