購物車
幫助
021-54845833/15800441009
相關(guān)類別： 一抗
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
技術(shù)規(guī)格
|
Background: |
Interferon regulatory factor 9 is a protein that in humans is encoded by the IRF9 gene, previously known as ISGF3G. Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. |
|
Applications: |
ELISA, WB |
|
Name of antibody: |
IRF9 |
|
Immunogen: |
Fusion protein of human IRF9 |
|
Full name: |
interferon regulatory factor 9 |
|
Synonyms： |
p48; IRF-9; ISGF3; ISGF3G |
|
SwissProt: |
Q00978 |
|
ELISA Recommended dilution: |
1000-2000 |
|
WB Predicted band size: |
44 kDa |
|
WB Positive control: |
Mouse heart tissue |
|
WB Recommended dilution: |
200-1000 |
