購(gòu)物車
幫助
021-54845833/15800441009
儲(chǔ) 存： 冷凍（-2℃）
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Background: |
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ITGA5 |
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Immunogen: |
Fusion protein of human ITGA5 |
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Full name: |
integrin subunit alpha 5 |
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Synonyms: |
FNRA; CD49e; VLA-5; VLA5A |
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SwissProt: |
P08648 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human colorectal cancer |
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IHC Recommend dilution: |
25-100 |
