宿 主: Rabbit
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
IMPDH2 |
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Immunogen: |
Fusion protein of human IMPDH2 |
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Full name: |
IMP (inosine 5'-monophosphate) dehydrogenase 2 |
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Synonyms: |
IMPD2; IMPDH-II |
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SwissProt: |
P12268 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human lung cancer and human liver cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
56 kDa |
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WB Positive control: |
A549 cells |
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WB Recommended dilution: |
500-2000 |


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