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中文名稱：CLDN23抗原（重組蛋白）

英文名稱： CLDN23 Antigen (Recombinant Protein)

儲  存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to a region derived from 182-292 amino acids of human CLDN23


技術(shù)規(guī)格

Full name:

claudin 23

Synonyms:

CLDNL; hCG1646163

Swissprot:

Q96B33

Gene Accession:

BC125148

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in germinal center B-cells, placenta and stomach as well as in colon tumor. This gene is down-regulated in intestinal type gastric cancer.


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