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Background: |
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Applications: |
ELISA, IHC |
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Name of antibody: |
KARS1 |
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Immunogen: |
Fusion protein of human KARS1 |
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Full name: |
lysyl-tRNA synthetase 1 |
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Synonyms: |
KRS; KARS; KARS2; CMTRIB; DFNB89 |
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SwissProt: |
Q15046 |
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IHC positive control: |
Human brain and Human ovarian cancer |
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IHC Recommend dilution: |
50-200 |

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