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Background: |
This gene encodes a protein that belongs to a conserved family of potassium channel tetramerization domain (KCTD)-containing proteins. The encoded protein functions in ciliogenesis by acting as a substrate adaptor for the cullin3-based ubiquitin-conjugating enzyme E3 ligase, and targets trichoplein, a keratin-binding protein, for degradation via polyubiquitinylation. A mutation in this gene is associated with autosomal dominant myoclonic dystonia 26. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
KCTD17 |
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Immunogen: |
Fusion protein of human KCTD17 |
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Full name: |
potassium channel tetramerization domain containing 17 |
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SwissProt: |
Q8N5Z5 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human gastric cancer; |
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IHC Recommend dilution: |
10-50 |

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