Name: ACTL7B 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：ACTL7B 抗原（重組蛋白）

英文名稱： ACTL7B Antigen (Recombinant Protein)

別名： actin-like 7B; Tact1

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to C terminal 250 amino acids of human ACTL7B

技術(shù)規(guī)格：

Full name:	actin-like 7B
Synonyms:	Tact1
Swissprot:	Q9Y614
Gene Accession:	BC033789
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia.

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