Name: ADAM15 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：ADAM15 抗原（重組蛋白）

英文名稱： ADAM15 Antigen (Recombinant Protein)

別名： ADAM metallopeptidase domain 15; MDC15

儲存： 冷凍（-20℃）

相關(guān)類別：抗原

概述：

Fusion protein corresponding to a region derived from 213-414 amino acids of human ADAM15

技術(shù)規(guī)格：

Full name:	ADAM metallopeptidase domain 15
Synonyms:	MDC15
Swissprot:	Q13444
Gene Accession:	BC014566
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

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