Name: IFRD2 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：IFRD2 抗原（重組蛋白）

英文名稱： IFRD2 Antigen (Recombinant Protein)

別名： interferon related developmental regulator 2; SM15; IFNRP; SKMc15

儲存：冷凍（-20℃）

相關類別： 抗原

概述

Fusion protein corresponding to a region derived from 307-506 amino acids of human IFRD2

技術規(guī)格

Full name:	interferon related developmental regulator 2
Synonyms:	SM15; IFNRP; SKMc15
Swissprot:	Q12894
Gene Accession:	BC001676
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	IFRD2 (Interferon-related developmental regulator 2), also known as SKMC15, is a 442 amino acid soluble nuclear protein. IFRD2 is ubiquitously expressed and contains a β-catenin-like repeat, which may indicate an involvement in APC signaling. With 75% homology to IFRD1, IFRD2 may also regulate expression of surface adhesion molecules involved in differentiation and fusion of myogenic satellite cells. Although the gene encoding IFRD2 undergoes overlapping homozygous deletions in many lung cancer cell lines, IFRD2 exhibits no loss-of-function mutations in cancer cells, suggesting a possible role in tumor progression.

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