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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16183
    • 應(yīng)用 : 僅限于科研使用
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中文名稱： ARMC8 抗原（重組蛋白）
英文名稱： ARMC8 Antigen (Recombinant Protein)
別       名： armadillo repeat containing 8; GID5; VID28; S863-2; HSPC056
儲(chǔ)       存： 冷凍（-20℃）
相關(guān)類別： 抗原

概述

Fusion protein corresponding to a region derived from 186-385 amino acids of human ARMC8

技術(shù)規(guī)格

Full name:

armadillo repeat containing 8

Synonyms:

GID5; VID28; S863-2; HSPC056

Swissprot:

Q8IUR7

Gene Accession:

BC013424

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The armadillo (ARM) repeat family of proteins are related to the Drosophila melanogaster armadillo protein, a protein essential for wingless signal transduction. ARM proteins are involved in a variety of processes such as cell migration, cell proliferation, tissue maintenance and tumorigenesis, and they also function in signal transduction and the maintenance of overall cell structure. ARMC8 (armadillo repeat containing 8), also known as S863-2, is a 673 amino acid protein that contains 14 ARM repeats, suggesting a role in signal transduction events throughout the cell. Six isoforms of ARMC8 are expressed due to alternative splicing events. The gene encoding ARMC8 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.

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