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    • 品牌 : 通蔚生物
    • 目錄號 : TW16184
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中文名稱: CHIT1 抗原(重組蛋白)

英文名稱: CHIT1 Antigen (Recombinant Protein)

別     名: chitinase 1; CHI3; CHIT; CHITD

儲     存: 冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Fusion protein corresponding to a region derived from 267-466 amino acids of human CHIT1

技術(shù)規(guī)格

Full name:

chitinase 1

Synonyms:

CHI3; CHIT; CHITD

Swissprot:

Q13231

Gene Accession:

BC103695

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.



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