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    • 品牌 : 通蔚生物
    • 目錄號 : TW16188
    • 應(yīng)用 : 僅限于科研使用
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    • 規(guī)格 ：1mg/100ug
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中文名稱： CHERP 抗原（重組蛋白）

英文名稱： CHERP Antigen (Recombinant Protein)

別     名： calcium homeostasis endoplasmic reticulum protein; SRA1; DAN16; SCAF6

儲     存： 冷凍（-20℃）

相關(guān)類別： 抗原

概    述

Fusion protein corresponding to a region derived from 738-916 amino acids of human CHERP

技術(shù)規(guī)格

Full name:

calcium homeostasis endoplasmic reticulum protein

Synonyms:

SRA1; DAN16; SCAF6

Swissprot:

Q8IWX8

Gene Accession:

BC021294

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The regulation of the intracellular concentration of calcium is important for proper maintenance of voltage-gated ion channels which control muscle and nerve function. Calcium homeostasis is regulated by a variety of proteins. CHERP (calcium homeostasis endoplasmic reticulum protein), also known as SRA1, DAN16 or SCAF6, is a 916 amino acid protein that localizes to the cytoplasm and the endoplasmic reticulum (ER). Expressed in pancreas, brain, lung, placenta, liver, kidney, heart and skeletal muscle, CHERP is involved in maintaining calcium homeostasis and plays a role in cell growth and proliferation. CHERP contains one G-patch domain, one RPR domain and one SURP motif and is expressed as two isoforms due to alternative splicing events.



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