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  • CYFIP1 抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW16447
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中文名稱： CYFIP1 抗原（重組蛋白）

英文名稱： CYFIP1 Antigen (Recombinant Protein)

別     名： cytoplasmic FMR1 interacting protein 1; SHYC; SRA1; SRA-1; P140SRA-1

儲     存： 冷凍（-20℃）

相關類別： 抗原

概     述

Fusion protein corresponding to a region derived from 1101-1253 amino acids of human CYFIP1

技術規(guī)格

Full name:

cytoplasmic FMR1 interacting protein 1

Synonyms:

SHYC; SRA1; SRA-1; P140SRA-1

Swissprot:

Q7L576

Gene Accession:

BC005097

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers.



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