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  • CD33抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16903
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
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中文名稱:  CD33抗原(重組蛋白)

英文名稱: CD33 Antigen (Recombinant Protein)

別       名 p67; SIGLEC3; SIGLEC-3

儲(chǔ)       存 冷凍(-20℃)

相關(guān)類別:抗原

概  述:

Fusion protein corresponding to a region derived from 18-259 amino acids of human CD33


技術(shù)規(guī)格: 

Full name:

CD33 molecule

Synonyms:

p67; SIGLEC3; SIGLEC-3

Swissprot:

P20138

Gene Accession:

BC028152

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).