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021-54845833/15800441009
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Full name: |
microtubule-associated protein tau |
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Synonyms: |
TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17 |
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Swissprot: |
P10636 |
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Gene Accession: |
BC114948 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. |
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