Name: BUB1抗原（重組蛋白）
Brand: 通蔚生物

中文名稱(chēng)： BUB1抗原（重組蛋白）

英文名稱(chēng)： BUB1 Antigen (Recombinant Protein)

別名： BUB1A; BUB1L; hBUB1

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類(lèi)別： 抗原

概述：

Fusion protein corresponding to a region derived from 281-419 amino acids of human BUB1

技術(shù)規(guī)格：

Full name:	BUB1 mitotic checkpoint serine/threonine kinase
Synonyms:	BUB1A; BUB1L; hBUB1
Swissprot:	O43683
Gene Accession:	BC028201
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.

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