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    • 品牌 : 通蔚生物
    • 目錄號 : TW16888
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中文名稱：CBR1抗原（重組蛋白）

英文名稱： CBR1 Antigen (Recombinant Protein)

別      名： CBR; hCBR1; SDR21C1

儲      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概  述：

Fusion protein corresponding to a region derived from 2-277 amino acids of human CBR1


技術(shù)規(guī)格：

Full name:

carbonyl reductase 1

Synonyms:

CBR; hCBR1; SDR21C1

Swissprot:

P16152

Gene Accession:

BC002511

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.



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