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    • 品牌 : 通蔚生物
    • 目錄號 : TW5886
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中文名稱: TYR 抗原(重組蛋白)

英文名稱: TYR Antigen (Recombinant Protein)

相關(guān)類別:抗原

儲     存: 冷凍(-20℃)

概     述

Fusion protein corresponding to a region derived from 19-319 amino acids of human TYR

技術(shù)規(guī)格

Full name:

Tyrosinase

Synonyms:

CMM8; OCA1A; OCAIA; SHEP3

Swissprot:

P14679

Gene Accession:

BC027179

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.



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