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中文名稱:EIF2AK4抗原(重組蛋白)

英文名稱 EIF2AK4 Antigen (Recombinant Protein)

別      名: GCN2; PVOD2

儲      存: 冷凍(-20℃)

相關類別: 抗原

概  述:

Fusion protein corresponding to a region derived from 1400-1649 amino acids of human EIF2AK4


技術規(guī)格:

Full name:

eukaryotic translation initiation factor 2 alpha kinase 4

Synonyms:

GCN2; PVOD2

Swissprot:

Q9P2K8

Gene Accession:

BC009350

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.


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