Name: SIRT1抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：SIRT1抗原（重組蛋白）

英文名稱： SIRT1 Antigen (Recombinant Protein)

別名： SIR2L1

儲存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to C terminal 250 amino acids of human SIRT1

技術(shù)規(guī)格

Full name:	sirtuin 1
Synonyms:	SIR2L1
Swissprot:	Q96EB6
Gene Accession:	BC012499
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

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