Name: SKP1抗原（重組蛋白）
Brand: 通蔚生物

中文名稱(chēng)： SKP1抗原（重組蛋白）

英文名稱(chēng)： SKP1 Antigen (Recombinant Protein)

別名： OCP2, p19A, EMC19, SKP1A, OCP-II, TCEB1L

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類(lèi)別：抗原

概述

Fusion protein corresponding to N terminal 163 amino acids of human SKP1

技術(shù)規(guī)格

Full name:	S-phase kinase-associated protein 1
Synonyms:	OCP2, p19A, EMC19, SKP1A, OCP-II, TCEB1L
Swissprot:	P63208
Gene Accession:	BC009839
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

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