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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17309
    • 應(yīng)用 : 僅供科研使用
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中文名稱： TP73抗原（重組蛋白）

英文名稱： TP73 Antigen (Recombinant Protein)

別       名： P73

儲(chǔ)       存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述

Fusion protein corresponding to a region derived from 131-310 amino acids of human TP73

技術(shù)規(guī)格

Full name:

tumor protein p73

Synonyms:

P73

Swissprot:

O15350

Gene Accession:

BC117251

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.

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