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    • 品牌 : 通蔚生物
    • 目錄號 : TW17389
    • 應(yīng)用 : 僅供科研使用
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    • 規(guī)格 ：100ug
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中文名稱：MGP 抗原（重組蛋白）

英文名稱： MGP Antigen (Recombinant Protein)

別       名： matrix Gla protein; NTI; GIG36; MGLAP

儲       存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to a region derived from 20-103 amino acids of human MGP

技術(shù)規(guī)格

Full name:

matrix Gla protein

Synonyms:

NTI; GIG36; MGLAP

Swissprot:

P08493

Gene Accession:

BC005272

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the osteocalcin/matrix Gla family of proteins. The encoded vitamin K-dependent protein is secreted by chondrocytes and vascular smooth muscle cells, and functions as a physiological inhibitor of ectopic tissue calcification. Carboxylation status of the encoded protein is associated with calcification of the vasculature in human patients with cardiovascular disease and calcification of the synovial membranes in osteoarthritis patients. Mutations in this gene cause Keutel syndrome in human patients, which is characterized by abnormal cartilage calcification, peripheral pulmonary stenosis and facial hypoplasia.

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