Name: KLC1抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：KLC1抗原（重組蛋白）

英文名稱： KLC1 Antigen (Recombinant Protein)

別名： KLC; KNS2; KNS2A

儲存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to N terminal 213 amino acids of human KLC1

技術(shù)規(guī)格：

Full name:	kinesin light chain 1
Synonyms:	KLC; KNS2; KNS2A
Swissprot:	Q07866
Gene Accession:	BC008881
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.

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