Name: STK17B抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：STK17B抗原（重組蛋白）

英文名稱： STK17B Antigen (Recombinant Protein)

別名： DRAK2

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to a region derived from 33-293 amino acids of human STK17B

技術(shù)規(guī)格：

Full name:	serine/threonine kinase 17b
Synonyms:	DRAK2
Swissprot:	O94768
Gene Accession:	BC016040
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The full-length STK17B cDNA clone encodes a deduced 372-amino acid protein with a molecular mass of 42.34 kD. The putative kinase domain is located at the N terminus and contains all 11 subdomains conserved among ser/thr kinases. STK17A and STK17B share 59.7% amino acid identity. Northern blot analysis revealed that STK17B was expressed in various tissues, such as heart, placenta, liver, and pancreas, as different-sized transcripts, presumably due to differences in the 3-prime untranslated region. Transient transfection of COS-7 cells showed that STK17B localized in nuclei. Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis.

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