Name: ORMDL3抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： ORMDL3抗原（重組蛋白）

英文名稱： ORMDL3 Antigen (Recombinant Protein)

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Full length fusion protein

技術規(guī)格

Full name:	ORMDL sphingolipid biosynthesis regulator 3
Swissprot:	Q8N138
Gene Accession:	BC000638
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling. SNPs on 17q21 locus that are associated with childhood asthma also show a consistent and strong association with transcript levels of ORMDL3, indicating that genetic variants regulating ORMDL3 expression are determinants of susceptibility to childhood asthma.

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