Name: IRF8抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：IRF8抗原（重組蛋白）

英文名稱： IRF8 Antigen (Recombinant Protein)

別名： ICSBP; IRF-8; ICSBP1; IMD32A; IMD32B; H-ICSBP

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述

Fusion protein corresponding to a region derived from 127-426 amino acids of human IRF8

技術(shù)規(guī)格

Full name:	interferon regulatory factor 8
Synonyms:	ICSBP; IRF-8; ICSBP1; IMD32A; IMD32B; H-ICSBP
Swissprot:	Q02556
Gene Accession:	BC126247
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.

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