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    • 品牌 : 通蔚生物
    • 目錄號 : TW18284
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    • 規(guī)格 :1mg/100ug
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中文名稱:  MARCHF2 抗原(重組蛋白)

英文名稱: MARCHF2 Antigen (Recombinant Protein)

別      名: membrane associated ring-CH-type finger 2; MARCH2; RNF172; HSPC240; MARCH-II

相關(guān)類別: 抗原

儲      存: 冷凍(-20℃) 

概      述

Fusion protein corresponding to a region derived from 1-246 amino acids of human MARCHF2


技術(shù)規(guī)格

Full name:

membrane associated ring-CH-type finger 2

Synonyms:

MARCH2; RNF172; HSPC240; MARCH-II

Swissprot:

Q9P0N8

Gene Accession:

BC111388

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]; Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM, Mar 2010]


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