Name: PCNA抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： PCNA抗原（重組蛋白）

英文名稱： PCNA Antigen (Recombinant Protein)

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to a region derived from 8-256 amino acids of human PCNA

技術規(guī)格

Full name:	Proliferating cell nuclear antigen
Synonyms:	ATLD2
Swissprot:	P12004
Gene Accession:	BC000491
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome

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