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中文名稱：PAPSS2抗原（重組蛋白）

英文名稱： PAPSS2 Antigen (Recombinant Protein)

別      名： SK2; BCYM4; ATPSK2

儲(chǔ)      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概      述：

Fusion protein corresponding to a region derived from 467-614 amino acids of human PAPSS2


技術(shù)規(guī)格：

Full name:

3'-phosphoadenosine 5'-phosphosulfate synthase 2

Synonyms:

SK2; BCYM4; ATPSK2

Swissprot:

O95340

Gene Accession:

BC009894

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.


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