中文名稱:PPP1R1A抗原(重組蛋白)
英文名稱: PPP1R1A Antigen (Recombinant Protein)
別 名: I1; IPP1
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
|
Fusion protein corresponding to a region derived from 1-171 amino acids of human PPP1R1A |
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Full name: |
protein phosphatase 1 regulatory inhibitor subunit 1A |
|
Synonyms: |
I1; IPP1 |
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Swissprot: |
Q13522 |
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Gene Accession: |
BC022470 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. |
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