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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW18379
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中文名稱:QDPR 抗原(重組蛋白)

英文名稱: QDPR Antigen (Recombinant Protein)

別      名: quinoid dihydropteridine reductase; DHPR; PKU2; HDHPR; SDR33C1

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概      述:

Fusion protein corresponding to a region derived from 2-244 amino acids of human QDPR


技術(shù)規(guī)格:

Full name:

quinoid dihydropteridine reductase

Synonyms:

DHPR; PKU2; HDHPR; SDR33C1

Swissprot:

P09417

Gene Accession:

BC000576

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.


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