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  • ZAP70抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW18487
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱:ZAP70抗原(重組蛋白)

英文名稱: ZAP70 Antigen (Recombinant Protein)

別      名: SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概      述:

Fusion protein corresponding to a region derived from 420-619 amino acids of human ZAP70


技術(shù)規(guī)格:

Full name:

zeta chain of T cell receptor associated protein kinase 70

Synonyms:

SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70

Swissprot:

P43403

Gene Accession:

BC039039

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.