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中文名稱:ZFYVE27抗原(重組蛋白)

英文名稱: ZFYVE27 Antigen (Recombinant Protein)

別      名: SPG33; PROTRUDIN

儲      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概       述:

Fusion protein corresponding to a region derived from 212-411 amino acids of human ZFYVE27


技術(shù)規(guī)格:

Full name:

zinc finger FYVE-type containing 27

Synonyms:

SPG33; PROTRUDIN

Swissprot:

Q5T4F4

Gene Accession:

BC030621

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.


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