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Background: |
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
EIF2B3 |
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Immunogen: |
Fusion protein of human EIF2B3 |
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Full name: |
eukaryotic translation initiation factor 2B subunit gamma |
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Synonyms: |
EIF-2B; EIF2Bgamma |
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SwissProt: |
Q9NR50 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer and Human esophagus cancer |
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IHC Recommend dilution: |
100-200 |

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