Name: MYD88抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： MYD88抗原（重組蛋白）

英文名稱： MYD88 Antigen (Recombinant Protein)

別名： MYD88D

儲存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Full length fusion protein

技術(shù)規(guī)格

Full name:	myeloid differentiation primary response 88
Synonyms:	MYD88D
Swissprot:	Q99836
Gene Accession:	BC013589
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

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