Name: NDUFB11抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： NDUFB11抗原（重組蛋白）

英文名稱： NDUFB11 Antigen (Recombinant Protein)

別名： ESSS; Np15; P17.3; NP17.3; CI-ESSS; LSDMCA3

儲存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Full length fusion protein

技術(shù)規(guī)格

Full name:	NADH:ubiquinone oxidoreductase subunit B11
Synonyms:	ESSS; Np15; P17.3; NP17.3; CI-ESSS; LSDMCA3
Swissprot:	Q9NX14
Gene Accession:	BC010665
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUFB11 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11), also known as ESSS, Np15, Np17.3 (neuronal protein 17.3) or p17.3, is a hydrophobic transmembrane protein belonging to the Complex I NDUFB11 subunit family. Ubiquitously expressed, NDUFB11 localizes to the inner membrane of the mitochondrion and functions as an accessory subunit of Complex I. The cAMP-dependent phosphorylation of NDUFB11 is important for the regulation of Complex I activity.

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