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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW19566
    • 應(yīng)用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 ：1mg/100ug
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中文名稱： PKM抗原（重組蛋白）

英文名稱： PKM Antigen (Recombinant Protein)

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 11-221 amino acids of human PKM

技術(shù)規(guī)格

Full name:

pyruvate kinase, muscle

Synonyms:

PK3; TCB; OIP3; PKM2; CTHBP; THBP1; HEL-S-30

Swissprot:

P14618

Gene Accession:

BC007640

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.



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