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中文名稱： 兔抗NR1H3多克隆抗體
英文名稱： Anti-NR1H3 rabbit polyclonal antibody
別 名： LXR-a; LXRA; RLD-1
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： NR1H3
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
WB |
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Name of antibody: |
NR1H3 |
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Immunogen: |
Fusion protein of human NR1H3 |
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Full name: |
nuclear receptor subfamily 1, group H, member 3 |
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Synonyms： |
LXR-a; LXRA; RLD-1 |
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SwissProt: |
Q13133 |
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WB Predicted band size: |
50 kDa |
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WB Positive control: |
MCF7 cells |
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WB Recommended dilution: |
500-2000 |
